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 | Seeking Glue-free and Plastic-free closure of paper packaging |
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We are looking for a technology to seal paper packaging materials (paper only with no plastic coating) without using traditional glues or any other additive. For a sustainable packaging application, we're looking for a technology to seal or crimp kraft paper without using glue or plastic coating applied on the paper. Ideally, we want to seal 100% untreated paper without adding any other chemicals. Our preferred solution would be a folding of the packaging material |
 | Seeking Recyclable Closure for Paper Beverage Bottles |
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We are seeking technologies for a re-closable fiber-based closure for a paper beverage bottle that can be recycled in the paper stream. |
 | Seeking existing market solutions targeted towards crawling insects |
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The issue of crawling insects in homes has been an ongoing issue. The popular types of crawling insects causing problems have been ants and cockroaches. The search will focus on existing market solutions targeted towards crawling insects such as ants and cockroaches (other types of crawling insects are in scope i.e., bed bugs). |
 | Sling for paretic limb - Special aid for patients after stroke or brachial plexus injury |
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Paresis of the upper limb is one of the most common consequences of a stroke or brachial plexus injury. Patients have difficulties controlling the paretic limb, especially against gravity so it can create overloading-induced soft tissue damage in the shoulder area, which can lead to the painful shoulder syndrome. Reduced ability of paretic upper limb to perform functional movements (e.g., reaching, grasping, and manipulating an object) leads to difficulties in performing daily activities and dependence of the individual on the help of others. In addition to the irreplaceable role of intensive rehabilitation, temporary positioning of the limb is necessary. For this, rehabilitation aids are used to improve the user’s self-service and quality of life. Common solution for positioning paretic upper limb are currently, for example, a non-woven triangular bandage or a „bag“ type arm sling in which the forearm is placed in a soft „bag“ with a free wrist. However, these aids can overload the cervical spine and cause pain, while at the same time, it can be difficult for the patient to fix the paretic limb in such aids by himself. Our invention is intended to be used for simple fixation of the paretic upper limb in the ideal position without the need to be hung over the neck area. The aid is intended to be used for temporary period, until the patient’s condition stabilizes, and he can already be equipped with a suitable orthosis or for a temporary period until the function of the upper limb improves. The positioning sling fixes the elbow joint and the wrist of the handicapped upper limb into a „pocket“, which forms a support and ensures the ideal position of the limb by preventing damage to the muscles and joints of the upper limb. Thanks to the elastic part, there is no overloading in the shoulder area and the sling does not slip and fits well. The sling can put on by the patient himself, thus increasing patient’s self-service and quality of life during recovery. The sling is suitable for patients after a stroke, with brachial plexus paresis, peripheral paresis and after injuries of the upper limb, where temporary positioning is necessary. It can also be used, for example, in Sudeck syndrome, which is associated, among other things, with the development of edema. The use of a sling ensures a smaller bend in the elbow joint and a better lymphatic drainage of the upper limb, thus reducing the edema, enabling better rehabilitation process and minimizing the occurrence of secondary problems. After being given instructions, the patient usually manages to put the device on the limb by himself. Main advantege is its simplicity - setting the appropriate length of the sling using velcro makes aid universal and efficient during recovery, it also improves patient’s self-service during daily activities. It is also easy to handle, which was confirmed by social workers and medical staff. It can be used both in home and institutional care. |
 | Stable inhibitors of the 5-lipoxygenase pathway for treating Asthma and Cancer |
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The University of Leipzig has patented a series of Carborane-Based Inhibitors of the 5-LO Lypoxygenase pathway. These inhibitors are selectively cytotoxic towards several leukotriene-dependend melanoma and colon cancer cell lines., while leaving non-malignent cells intact. Furthermore, these inhibitor analogues have shown co-inhibition of heat shock proteins necessary for tumor development in such cell lines. Experimental results on mice showed promising results. Moreover, since these compounds have a high content of boron, they may also be suitable for Boron Neutron Capture Therapy (BNCT), a binary cancer therapy that uses selective boron compounds and thermal neutrons. Furthermore, leukotriene inhibition could be useful in the treatment of asthma, as their production is related to inflammatory responses. The BBZ is looking for organzations interested in acquiring this technology offer, helping perform precilinical and clinical studies, and ultimately leading to the licensing of it. |
 | Polycarbonate-Urethane Coated Universal Talus Implant |
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● A series of universal-geometry talus implants with different sizes have been created. ● Polycarbonate-Urethane (PCU) coatings may simulate natural cartilage on implants. ● PCU coated implants may reduce the risk of cartilage wear and bone fracture for talus implants. |
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